Immunomodulatory activity of methanolic fruit extract of Aegle marmelos in experimental animals

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Immunomodulatory Potential of Methanol Extract of Aegle marmelos in Animals

The aim of the current research was to evaluate the immunomodulatory potential of methanol extract of Aegle marmelos in an experimental animal model of cellular and humoral immunity. Administration of methanol extract of Aegle marmelos (500 and 1000 mg/kg, p.o.) and Ocimum sanctum (100 mg/kg, p.o.), produced significant increase in adhesion of neutrophils and an increase in phagocytic index in ...

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Simultaneous quantification of furanocoumarins from Aegle marmelos fruit pulp extract.

Aegle marmelos Correa (Rutaceae) is a prominent species in the Sub-Himalayan region, also found in central and south India, and has been widely used as remedy for diarrhea and dysentery. Unripe fruits show antiviral activity and prove to be a potent hypoglycemic agent. In this study, a high-performance liquid chromatography (HPLC) method for the simultaneous quantification of major furocoumarin...

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Anti-microfilarial activity of methanolic extract of Vitex negundo and Aegle marmelos and their phytochemical analysis.

In the present study, methanolic extracts of roots of Vitex negundo L. and extracts of leaves of Vitex negundo L., Ricinus communis L. and Aegle marmelos Corr. were explored for possible antifilarial effect against Brugia malayi microfilariae. It was observed that among the herbal extracts, root extract of Vitex negundo L. and leaves extract of Aegle marmelos Corr. at 100 ng/ml concentration sh...

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Healing effects of Aegle marmelos (L.) Correa fruit extract on experimental colitis.

Graded doses of 50% ethanolic extract of dried fruit pulp of Aegle marmelos (AME) (100, 200 and 400 mg/kg) daily for 14 days in acetic acid (AA)-induced colitis in rats showed 200 mg/kg of AME as an optimal effective dose against AA-induced colonic damage score and weight. This dose (200 mg/kg; po) was further studied in AA-induced colitis for its effects on various physical (mucous/blood in st...

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Experimental Evaluation of Diuretic Activity of Aegle Marmelos in Rats

Purpose: The aim of the present study was to investigate the diuretic activity of ethanolic extracts and its fractions of Aegle marmelos fruit in experimental models. Ethanolic extracts and its fractions of Aegle marmelos ripe fruit were administered to experimental rats intraperitonealy at doses of 300, 400 and 500 mg/kg i. p. Control group received only normal saline (25ml/kg) through intrape...

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ژورنال

عنوان ژورنال: Saudi Pharmaceutical Journal

سال: 2010

ISSN: 1319-0164

DOI: 10.1016/j.jsps.2010.05.006